Molecular body guards for neurons

A new publication by EPITARGET partner Bonn University Hospital has been published in The Journal of Neuroscience. The researchers of Bonn University Hospital uncover an important link in a neuroprotective signal cascade

In the brain, patterns of neural activity are perfectly balanced. The interplay between activating and inhibitory neurotransmitters ensures that the level of activity stays within the physiological range. During an epileptic attack excitation gains the upper hand resulting in the death of neurons. Researchers of the EPITARGET partner Bonn University Medical School have now discovered a key player in a signal transduction cascade, which protects neurons from hyperexcitation-induced cell death. These results open a new direction for the development of novel therapy options. The results are now published in „The Journal of Neuroscience“.